Drug Discovery & Development
11.7T MR spectroscopy quantifies brain glucose metabolism
French researchers have developed a new MR (magnetic resonance) spectroscopy approach to study brain glucose metabolism, a process significantly involved in Alzheimer's disease. They presented their work in an animal study at the annual meeting of the International Society for Magnetic Resonance in Medicine. Read More
Manufacturing partnerships support high quality cell therapies
Chimeric Therapeutics, Ncardia, and Novartis are some of the companies that have decided to partner to make complex manufacturing processes more efficient for novel therapies, according to Cell and Gene Therapy Business Outlook, a sister publication of ScienceBoard. Read More
New mutational signatures pinpoint causes of cancer and personalize treatment
New research published on April 11 in Cancer Research has revealed a previously unknown mechanism in a common form of lung cancer that uses epigenetic regulation to avoid the effect of treatment. Read More
Advances in gene therapy call for education, patient advocate says
Durhane Wong-Rieger, board chair of Rare Diseases International, spoke to ScienceBoard.net at the Cell & Gene Meeting on the Med last week in Barcelona, Spain, following a panel on trends and challenges in gene therapy. Read More
MASTER technology could transform CAR T-cell therapy
A new technology that helps CAR T cells attack cancer cells more aggressively than conventional methods has been published by researchers from North Carolina. Called multifunctional alginate scaffold for T-cell engineering and release (MASTER), the technology was described in a paper published on March 24 in Nature Biotechnology. Read More
Nivolumab/chemo combo will change lung cancer care
A new study that pairs neoadjuvant nivolumab with chemotherapy for patients with nonsmall cell lung cancer has the potential to revolutionize treatment, according to one expert. The research was presented April 11 at the American Association for Cancer Research 2022 meeting and published simultaneously in the New England Journal of Medicine. Read More
CAR T-cells show preliminary efficacy, safety as solid-tumor treatment
Researchers presented phase I/II preliminary clinical trial data demonstrating the safety and efficacy of a new CAR T-cell therapy that can be used as either a monotherapy or a combination therapy to treat Claudin 6-positive solid tumors. The findings were presented at the American Association for Cancer Research Annual Meeting 2022 in New Orleans. Read More
Video from AACR 2022: Next-gen pathology tools for cancer research
NEW ORLEANS - What do the next-generation of pathology tools for cancer research look like, and how can pathologists contribute to those technologies to make an impact in their discipline? Dr. Beatrice Knudsen, PhD, of the Huntsman Cancer Institute at the University of Utah, explored these ideas at the American Association for Cancer Research (AACR) meeting in a video update from day two of the conference. Read More
Can AI predict adverse events from new drug combinations?
A new artificial intelligence (AI) model may be able to help clinicians predict if new combinations of drugs will produce side effects that are worse than their potential benefit, according to research presented at this week’s annual meeting of the American Association for Cancer Research. Read More
Biomedical innovations bring hope to patients with musculoskeletal diseases
Geistlich Biomaterials Italia, Santhera Pharmaceuticals, and Sarepta Therapeutics have entered into a series of collaborations to develop innovative strategies for treating musculoskeletal diseases, ranging from gene therapy to regenerative medicine, according to a recent report in Cell and Gene Therapy Business Outlook, a sister publication of ScienceBoard. Read More
Conferences
International Society for Cell and Gene Therapy Annual Meeting
May 4 - June 7
San Francisco, California United States
Interphex 2022 Conference
May 24-26
New York, New York United States
American Society for Mass Spectrometry Annual Conference
June 5-9
Minneapolis, Minnesota United States
American Society for Microbiology Microbe Meeting
June 9-13
District of Columbia United States
HPLC 2022
June 18-23
San Diego, California United States
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