Genomics
Large-scale WGS of thousands of cancers find previously unreported mutational signatures
Large-scale whole-genome sequencing (WGS) of thousands of cancers has found previously unreported mutational signatures, including tumor-specific rare signatures, according to research published on April 21 in Science. Read More
Illumina brings whole-genome sequencing to German hospital
Illumina has signed an agreement with Hannover Medical School in Germany to assess the use of rapid whole-genome sequencing (rWGS) in critically ill children suspected of having a genetic or rare disease. Read More
Meeting on the Med opens with new data and eyes on the money
BARCELONA, SPAIN -- The Cell & Gene Meeting on the Med conference kicked off on April 20 as speakers assessed the current state of the cell and gene therapy sector and explored payment strategies for advanced therapies across the European Union. Read More
Nivolumab/chemo combo will change lung cancer care
A new study that pairs neoadjuvant nivolumab with chemotherapy for patients with nonsmall cell lung cancer has the potential to revolutionize treatment, according to one expert. The research was presented April 11 at the American Association for Cancer Research 2022 meeting and published simultaneously in the New England Journal of Medicine. Read More
CAR T-cells show preliminary efficacy, safety as solid-tumor treatment
Researchers presented phase I/II preliminary clinical trial data demonstrating the safety and efficacy of a new CAR T-cell therapy that can be used as either a monotherapy or a combination therapy to treat Claudin 6-positive solid tumors. The findings were presented at the American Association for Cancer Research Annual Meeting 2022 in New Orleans. Read More
CRISPR technique may lead to hypoallergenic cats
Love cats but have allergies? Rejoice! Scientists have demonstrated that CRISPR gene editing of the cat allergen, Felis domesticus allergen I, could bring relief to those with cat allergies, according to a proof-of-concept study published online in the CRISPR Journal. Read More
Biomedical innovations bring hope to patients with musculoskeletal diseases
Geistlich Biomaterials Italia, Santhera Pharmaceuticals, and Sarepta Therapeutics have entered into a series of collaborations to develop innovative strategies for treating musculoskeletal diseases, ranging from gene therapy to regenerative medicine, according to a recent report in Cell and Gene Therapy Business Outlook, a sister publication of ScienceBoard. Read More
Scientists sequence complete human genome for the 1st time
A team of nearly 100 scientists from the Telomere-to-Telomere Consortium has for the first time unveiled the complete human genome. The findings were published on March 31 in the journal Science. Read More
Gene therapy shows long-term benefits for children with WAS
A lentiviral-based gene therapy treatment for children with Wiskott-Aldrich Syndrome (WAS) has demonstrated long-term benefits, according to research recently published in Nature Medicine. The findings demonstrate a safe alternative to the traditional treatment protocol. Read More
Bacteria don invisibility cloak to fight cancer
Using bacteria to target tumors is a promising avenue for developing new treatments, although the risk of severe side effects is holding back clinical trials. Now, in a new study published on March 17 in Nature Biotechnology, researchers have developed a way to reversibly hide the microbes from the immune system, providing control over their growth. Read More
Conferences
International Society for Cell and Gene Therapy Annual Meeting
May 4 - June 7
San Francisco, California United States
Interphex 2022 Conference
May 24-26
New York, New York United States
American Society for Mass Spectrometry Annual Conference
June 5-9
Minneapolis, Minnesota United States
American Society for Microbiology Microbe Meeting
June 9-13
District of Columbia United States
HPLC 2022
June 18-23
San Diego, California United States
Connect
Science Advisory Board on LinkedIn
Science Advisory Board on Facebook
Science Advisory Board on Twitter