Researchers identify genomic variants for rare genetic skin disorder Researchers used genome sequencing to identify the genomic variants that cause disabling pansclerotic morphea, a rare and serious inflammatory skin disorder. The results, published Wednesday in the New England Journal of Medicine, may point the way to a treatment, the researchers said.Read More
Deep sequencing captures genetic variants for vascular anomalies Children’s Hospital of Philadelphia (CHOP) researchers found that deep sequencing of the genome in the tissue samples and cell-free DNA of patients with potentially life-threatening vascular anomalies revealed genetic variants previously not captured by conventional genetic sequencing methods. The research, published Thursday in the journal Nature Medicine, led to improvements in over 60% of the patients placed on targeted therapies related to these newly found genetic variants.Read More
Gene editing tool may reduce antimicrobial resistance spread A tool that could help reduce the spread of antimicrobial resistance shows early promise. In an article published Thursday in Microbiology, researchers describe the use of CRISPR technology to eliminate resistance in a wide range of bacteria.Read More