Proteomics
MASTER technology could transform CAR T-cell therapy
A new technology that helps CAR T cells attack cancer cells more aggressively than conventional methods has been published by researchers from North Carolina. Called multifunctional alginate scaffold for T-cell engineering and release (MASTER), the technology was described in a paper published on March 24 in Nature Biotechnology. Read More
CAR T-cells show preliminary efficacy, safety as solid-tumor treatment
Researchers presented phase I/II preliminary clinical trial data demonstrating the safety and efficacy of a new CAR T-cell therapy that can be used as either a monotherapy or a combination therapy to treat Claudin 6-positive solid tumors. The findings were presented at the American Association for Cancer Research Annual Meeting 2022 in New Orleans. Read More
Gene therapy shows long-term benefits for children with WAS
A lentiviral-based gene therapy treatment for children with Wiskott-Aldrich Syndrome (WAS) has demonstrated long-term benefits, according to research recently published in Nature Medicine. The findings demonstrate a safe alternative to the traditional treatment protocol. Read More
LabCentral Ignite receives $400K grant to improve diversity in STEM
LabCentral Ignite has been awarded $400,000 in grants and matching awards from the U.S. Economic Development Administration and Breakthrough Properties, a life science real estate development company, to expand its Career Forge program. The nonprofit also announced that it is accepting applicants for its next Career Forge session. Read More
USCAP 2022: 4 tips for a more sustainable lab
LOS ANGELES -- The global biotechnology and pharmaceutical industry has a carbon footprint greater than even the forestry or paper industry, but there are ways scientists can help decrease their environmental impact, according to a keynote lecture at this week's United States and Canadian Academy of Pathology (USCAP) 2022 meeting. Read More
Cellular map of tissues created by combining sequencing techniques
Researchers have described an approach to combine single-cell sequencing experiments with spatial transcriptomics to create maps of tissues according to cell type, according to new research published on March 21 in the journal Nature Biotechnology. Read More
Endosomal pH drives stemness in glioblastoma
A group of researchers has shown that endosomal pH drives stemness in glioblastoma. The group discovered that endosomal Na+/H+ exchanger isoform 9 is a novel driver of stem cell-like characteristics -- or stemness -- in glioblastoma by stabilizing multiple receptor tyrosine kinases, according to a recent paper published in PNAS Nexus. Read More
'Roadmap' reveals how cells transform during mouse embryonic development
Mapping how complex animals develop from a single cell is a key area of study, but it remains a significant challenge. Now, research published in Nature Genetics on March 14, has laid out the molecular changes that control how cells transform during mouse embryonic development. The resulting roadmap identifies potential links between cell types to help understand the paths they take toward specialization. Read More
Targovax and Agenus team up on mutant KRAS cancer vaccine
Targovax and Agenus have entered into a clinical collaboration and supply agreement to combine Targovax's TG mutant KRAS cancer vaccines with Agenus' clinically validated and U.S. Food and Drug Administration-approved QS-21 Stimulon adjuvant. Read More
How diversity, inclusion help one company turn sci-fi into sci-fact
Juliana Blum, PhD, co-founder and executive vice president of corporate development at Humacyte, spoke with ScienceBoard about diversity and inclusion in the life sciences, especially about being a woman in science. Read More
Conferences
International Society for Cell and Gene Therapy Annual Meeting
May 4 - June 7
San Francisco, California United States
Interphex 2022 Conference
May 24-26
New York, New York United States
American Society for Mass Spectrometry Annual Conference
June 5-9
Minneapolis, Minnesota United States
American Society for Microbiology Microbe Meeting
June 9-13
District of Columbia United States
HPLC 2022
June 18-23
San Diego, California United States
Science Briefs
Conferences
International Society for Cell and Gene Therapy Annual Meeting
May 4 - June 7
San Francisco, California United States
Interphex 2022 Conference
May 24-26
New York, New York United States
American Society for Mass Spectrometry Annual Conference
June 5-9
Minneapolis, Minnesota United States
American Society for Microbiology Microbe Meeting
June 9-13
District of Columbia United States
HPLC 2022
June 18-23
San Diego, California United States
Connect
Science Advisory Board on LinkedIn
Science Advisory Board on Facebook
Science Advisory Board on Twitter