Beckman Coulter, Sciex collaborate on high-throughput screening workflows February 27, 2023 -- Life science analytical technologies company Sciex on Monday announced a collaboration with Beckman Coulter Life Sciences to provide comprehensive workflows for high-throughput screening; high-throughput absorption, distribution, metabolism, and excretion (HT-ADME); and synthetic biology studies.Read More
Nanozyme approach targets fungal infection May 31, 2023 -- A nanozyme-based robotics approach could allow doctors to target and kill fungal pathogens at the sites of infection, according to a group at the University of Pennsylvania.Read More
Stem cell therapy targets brain metastatic melanomas May 31, 2023 -- Twin stem cells acting in unison may activate the immune system to suppress metastatic melanoma tumor growth in the brain, according to Department of Defense-funded research, published Wednesday in Science Translational Medicine. The procedure prolonged survival in preclinical trials on mice, indicating that locally delivered immunotherapies may be beneficial in brain metastases treatment.Read More
Chemical compound stimulates nerve regeneration, protects heart tissue May 24, 2023 -- Researchers have identified a compound that can stimulate nerve regeneration after injury, as well as protect cardiac tissue from the type of damage seen in heart attacks. The study, published Wednesday in Nature, identified a chemical compound called 1938, which activates the signaling pathway of phosphoinositide 3-kinase (PI3K), an enzyme that helps control cell growth.Read More
COVID-19’s ‘long tail’ analyzed at European rheumatology congress May 31, 2023 -- Researchers have found that people with inflammatory rheumatic diseases show no increased susceptibility to long COVID. This and other studies are being presented at the European Alliance of Associations for Rheumatology (EULAR) 2023 Congress in Milan from May 31 to June 3.Read More
New antibiotic targets deadly hospital superbug May 25, 2023 -- Scientists used artificial intelligence (AI) to discover a promising antibiotic that may help doctors target Acinetobacter baumannii, a deadly, drug-resistant pathogen that often strikes vulnerable hospital patients. The study, published Thursday in the journal Nature Chemical Biology, identified the antibacterial compound abaucin in response to the urgent need for new ways to treat A. baumannii infection.Read More
Gene editing tool may reduce antimicrobial resistance spread May 26, 2023 -- A tool that could help reduce the spread of antimicrobial resistance shows early promise. In an article published Thursday in Microbiology, researchers describe the use of CRISPR technology to eliminate resistance in a wide range of bacteria.Read More
Scientists create cell atlas of developing human lung December 9, 2022 -- Researchers from the Wellcome Sanger Institute, EMBL’s European Bioinformatics Institute, the Gordone Institute at the University of Cambridge, and collaborators have created a spatiotemporal cell atlas of the developing human lung. From the mapping, they have identified 144 cell states in the early stages of life and their interactions in new detail.Read More
Senescent neuron discovery in brains opens path for Alzheimer's drug development December 2, 2022 -- Scientists at the Salk Institute for Biological Studies have found that neurons from people with Alzheimer's disease show deterioration and undergo a late-life stress process called cellular senescence, while senescent cells could be a way to slow neuroinflammation and neurodegeneration.Read More