Akadeum looks to advance the cell separation process with microbubbles
September 7, 2022 -- Microbubble technology offers researchers the ability to perform cell separation without a column or magnet, generating higher yield and faster turnaround times, according to Akadeum Life Sciences CEO Brandon McNaughton who spoke with ScienceBoard.net about the company's technology. Read More
ElevateBio, University of Pittsburgh awarded $100M grant to create biomanufacturing center
August 26, 2022 -- ElevateBio and the University of Pittsburgh have been awarded a $100 million grant from the Richard King Mellon Foundation to create the Pitt BioForge BioManufacturing Center at Hazelwood Green in Pittsburgh. Read More
Taking metformin during SARS-CoV-2 infection cuts risk of long COVID in clinical trial
June 9, 2023 -- People who took the diabetes drug metformin after being infected with SARS-CoV-2 were less likely to develop long COVID in a randomized clinical trial. Read More
Blood sugar maintenance mechanism revealed in DNA study
June 9, 2023 -- A large, worldwide DNA study has shed light on how healthy blood sugar levels are maintained after eating—and how that process may go wrong. The findings, published Thursday in Nature Genetics, may inform treatment for type 2 diabetes, which affects over 460 million people worldwide. Read More
Stem cell-loaded plug improves outcomes in hard-to-treat Crohn’s disease patients
March 3, 2023 -- Most Crohn’s disease patients experienced complete clinical healing of perianal fistulas after treatment with a stem cell-loaded plug, according to data published in the journal Diseases of the Colon & Rectum. Read More
At SLAS 2023, companies showcase, launch advanced automation and screening technologies
February 28, 2023 -- At the Society for Laboratory Automation and Screening (SLAS) 2023 International Conference and Exhibition, being held in San Diego from February 25 to March 1, numerous firms have announced that they are showcasing emerging technologies for advanced life science applications. Read More
HIV potentially cured by transplanting umbilical cord stem cells in mixed race woman
March 16, 2023 -- Transplanting stem cells from umbilical cord blood has potentially cured a mixed-race woman of HIV and freed her from taking antiviral medication, according to a case report published in Cell. Read More
Therapeutic target may aid in glaucoma treatment
March 13, 2023 -- Indiana University School of Medicine researchers have identified a new therapeutic target that could lead to more effective glaucoma treatment. The research, published recently in Communications Biology, found that restoring mitochondrial homeostasis in diseased neurons can protect optic nerve cells from being damaged. Read More
COVID-19 vaccine development: Public funding yielded private profits
March 1, 2023 -- Decades before the COVID-19 pandemic, the U.S. government invested at least $337 million into critical research that led to mRNA COVID-19 vaccines. The government also paid $31.6 billion during the pandemic for vaccine research, production, and vaccines for all Americans. Read More
Heart problems more likely among long COVID patients in comprehensive study
February 23, 2023 -- Individuals with long COVID were found to have more than double the risk of developing new cardiovascular symptoms. The results of a comprehensive study examining cardiovascular complications from long COVID will be presented at the American College of Cardiology Together with the World Congress of Cardiology (ACC.23/WCC) conference. The event, marking the ACC’s 72nd Annual Scientific Session, will take place March 4-6, both online and in New Orleans. Read More
New antibiotic targets deadly hospital superbug
May 25, 2023 -- Scientists used artificial intelligence (AI) to discover a promising antibiotic that may help doctors target Acinetobacter baumannii, a deadly, drug-resistant pathogen that often strikes vulnerable hospital patients. The study, published Thursday in the journal Nature Chemical Biology, identified the antibacterial compound abaucin in response to the urgent need for new ways to treat A. baumannii infection. Read More
Study of woman who cannot feel pain finds molecular explanation for phenomenon
May 24, 2023 -- Researchers have uncovered the biological effects of a mutation that causes its carrier to live virtually pain-free, heal more rapidly, and experience reduced anxiety and fear. Read More
Researchers map RNA to inform selection of stem cells for therapeutic applications
May 12, 2023 -- Creating maps of the RNA inside cells could improve cell therapies by enabling the isolation of subsets of cells with similar characteristics, according to a study published Friday in Cell Reports Methods. Read More
Synthego opens manufacturing facility for gene editing components
May 12, 2023 -- Genome engineering company Synthego on Thursday announced the opening of an 18,000 square-foot good manufacturing practice (GMP) synthesis facility for gene editing components. Read More
Study suggests immune response to anticancer checkpoint inhibitors unaffected by COVID-19 vaccination
February 1, 2023 -- Immune checkpoint inhibitors perform comparably in vaccinated and unvaccinated individuals, allaying concerns that injections given to protect against COVID-19 will interfere with cancer treatment. Read More
Marburg virus vaccine safe in small, first-in-human clinical trial: NIH
January 30, 2023 -- A study published in the Lancet on January 28 shows that an experimental vaccine against Marburg virus (MARV) was safe and induced an immune response in a small, first-in-human clinical trial. Read More
Scientists use new chemoproteomic method for global profiling of arginine dimethylation
October 20, 2022 -- A study published October 18 in the journal Proceedings of the National Academy of Sciences has revealed how arginine dimethylation regulates protein liquid-liquid phase separation and membraneless organelles by using a new chemoproteomic method. Read More
Benchtop single-molecule protein sequencing unlocks new way to study proteome
October 14, 2022 -- Life sciences company Quantum-Si has developed a benchtop instrument that performs single-molecule protein sequencing, setting the stage for a new approach to studying the proteome. Read More
Global consortium creates 'largest' zebrafish genetic atlas to support human disease research
July 5, 2022 -- An international consortium of 27 laboratories called DANIO-CODE has created an atlas of genetic data on zebrafish to support research into conditions including cancer, heart disease, and neurodegeneration. Read More
Single DNA strand cuts achieve safety and efficacy edge over CRISPR-Cas9 in fruit flies
July 5, 2022 -- CRISPR-Cas9 variants known as “nickases” that target a single DNA strand may increase the success rate of gene editing and reduce the risk of off-target mutations, according to a paper published in the journal Science Advances. Read More
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