New drug 'fakes out' SARS-CoV-2 to neutralize it
A new drug neutralizes SARS-CoV-2 and its variants by acting as an ACE2 receptor decoy, Dana-Farber Cancer Institute researchers revealed. Read More
Vaccines offer long-term protection against severe COVID-19 in monkeys
New research indicates that two-dose experimental SARS-CoV-2 vaccines provide protection against COVID-19-related lung disease in year-old rhesus macaques vaccinated as infants. Read More
Estrogen receptors plus COVID-19 spike proteins cause coagulopathy
The SARS-CoV-2 spike protein interacts with the human estrogen receptor alpha in lung tissue and that may lead to severe coagulopathy. This process demonstrates the virus's varied impact based on sex and a path to improved vaccines, a team of U.S. and European researchers found. Read More
Omicron subvariants dodge neutralizing antibodies: study
Three subvariants of SARS-CoV-2 currently sweeping through the U.S. are better at evading vaccine- and infection-generating neutralizing antibodies than earlier versions of the virus, new research finds. Read More
New protein target may help fight COVID-19
A University of Geneva-led research team revealed a hidden cavity on the surface of a key non-structural SARS-CoV-2 protein. Their research, published November 22 in the journal eLife, may facilitate this cavity’s use as a target for binding therapeutic drugs. Read More
Rapidly generated artificial enzymes inhibit COVID-19 infection in preclinical tests
Artificial enzymes targeting the SARS-CoV-2 genome can inhibit viral infection, pointing to a new way to rapidly develop treatments for emerging biological threats such as COVID-19. Read More
New drug may help fight both COVID-19 and cancer
Keck School of Medicine researchers and collaborators have discovered that GRP78, a protein implicated in both COVID-19 and various cancers, may also help fight both diseases. Read More
COVID-19 virus disrupts gut bacteria, increasing secondary infection risk
New research, led by New York University Grossman School of Medicine researchers, shows that SARS-CoV-2 infection reduces bacterial diversity in a patient's gut, creating opportunities for dangerous microbes to thrive. Read More
COVID-19 nasal vaccine bolsters immune response, drops transmission
Yale University scientists have concocted a new nasal vaccine that strengthens immune responses to COVID-19 in previously vaccinated animals and reduces viral transmission, which may help prevent breakthrough infections of vaccinated individuals. Read More
Research reveals mechanisms for SARS-CoV-2 infection in macrophages
Boston University researchers have identified a receptor that contributes to hyper-inflammatory responses to SARS-CoV-2 infection -- a finding that may potentially alleviate COVID-19 disease severity. Read More
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