Visualization of key step in protein production points to potential antibiotic target
Single-particle cryo-electron microscopy (cryo-EM) has visualized a key step in the production of proteins by bacteria, generating insights that could inform the development of new antibiotics. Read More
Chemical compound stimulates nerve regeneration, protects heart tissue
Researchers have identified a compound that can stimulate nerve regeneration after injury, as well as protect cardiac tissue from the type of damage seen in heart attacks. The study, published Wednesday in Nature, identified a chemical compound called 1938, which activates the signaling pathway of phosphoinositide 3-kinase (PI3K), an enzyme that helps control cell growth. Read More
Bacterial reaction to antibiotics revealed within minutes
A simple-to-use method reveals bacterial reaction to antibiotics in only five minutes. Read More
Researchers pitch cytokine-antibody complex as treatment for respiratory infections
Researchers have combined a cytokine and an antibody to generate inflammatory responses against viruses while minimizing tissue damage. Read More
Getting to know the Association of Biomolecular Resource Facilities (ABRF)
The Association of Biomolecular Resource Facilities (ABRF) will hold its Annual Meeting May 7 to May 10 in Boston. ABRF is a membership organization that brings together Core facilities across the U.S. and supports more than 2,400 members at over 400 institutions including organizations in government, academia, research, industry, and commercial settings. Over 50% of its members define their area of professional responsibility as either genomics or core administration. Read More
Opioid receptor analysis reveals way to treat pain without causing euphoria or hallucinations
The analysis of an opioid receptor has revealed a potential way to treat pain without causing addiction or hallucinations, two key barriers to the safe use of painkillers today. Read More
Lab-grown lung organoids may replace animal testing
Australian scientists have developed a blueprint to create lab-grown human mini-lung models. The research, published Wednesday in the journal Biomaterials Research, can accelerate the development of new drugs while reducing reliance on animal testing. Read More
Identification of cytokine that drives organ rejection points to better transplant drugs
Researchers have determined the mechanism that drives chronic organ transplant failure and have identified a potential way to stop the rejection process. Read More
Genetically engineered probiotic keeps mice sober, protects liver after alcohol exposure
A genetically engineered probiotic has accelerated recovery from alcohol exposure in mice, suggesting the approach could mitigate hangovers and adverse outcomes associated with excessive consumption. Read More
Discovery of first steps in drug resistance process reveals new targets for antibiotics
Scientists have revealed the initial mechanisms that give rise to drug-resistant Escherichia coli, pointing to potential targets for antibiotics that remain effective as bacteria mutate. Read More
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