Beckman Coulter teams with Flownamics on bioprocess culture monitoring
August 24, 2022 -- Beckman Coulter Life Sciences has partnered with Flownamics to offer an automated, online solution for bioprocess culture monitoring and control, meeting what the companies see as an unmet need in the current bioprocessing environment. Read More
NSF awards $6M to develop purification membranes for large-scale manufacturing of viral vectors
August 19, 2022 -- The National Science Foundation (NSF) has awarded a $6 million grant to researchers at the University of Arkansas and two partner institutions to develop purification membranes for future large-scale manufacturing of viral vectors and viruslike particles. Read More
Alzheimer’s disease and modifiable risk factors: Genetic associations revealed
May 17, 2023 -- A genetic association study comparing participants with Alzheimer’s disease and control participants without Alzheimer’s disease found novel genetic associations between high high-density lipoprotein (HDL) cholesterol concentrations and high systolic blood pressure and a higher risk of Alzheimer’s disease. Read More
Boundless Bio closes $100 million Series C financing to advance precision oncology therapies
May 17, 2023 -- Next-generation precision oncology company Boundless Bio on Tuesday announced the closing of its $100 million Series C financing, which will be used to advance the clinical development of its BBI-355 extrachromosomal DNA-directed oncology therapy. Read More
At SLAS 2023, companies showcase, launch advanced automation and screening technologies
February 28, 2023 -- At the Society for Laboratory Automation and Screening (SLAS) 2023 International Conference and Exhibition, being held in San Diego from February 25 to March 1, numerous firms have announced that they are showcasing emerging technologies for advanced life science applications. Read More
Beckman Coulter, Sciex collaborate on high-throughput screening workflows
February 27, 2023 -- Life science analytical technologies company Sciex on Monday announced a collaboration with Beckman Coulter Life Sciences to provide comprehensive workflows for high-throughput screening; high-throughput absorption, distribution, metabolism, and excretion (HT-ADME); and synthetic biology studies. Read More
Convert a smartphone into a fluorescent microscope for under $50
March 9, 2023 -- A few simple components can convert a smartphone or tablet into a fluorescent microscope for under $50 per unit. Read More
Improved gut-on-chip devices spur research into how the microbiome affects human health
March 1, 2023 -- Gut-on-chip devices can now simulate microbial and human cellular biology to enable the analysis of the microbiome, according to a study published in APL Bioengineering. Read More
Heart problems more likely among long COVID patients in comprehensive study
February 23, 2023 -- Individuals with long COVID were found to have more than double the risk of developing new cardiovascular symptoms. The results of a comprehensive study examining cardiovascular complications from long COVID will be presented at the American College of Cardiology Together with the World Congress of Cardiology (ACC.23/WCC) conference. The event, marking the ACC’s 72nd Annual Scientific Session, will take place March 4-6, both online and in New Orleans. Read More
Meta-analysis reveals roadmap for effective use of convalescent plasma in pandemics
February 21, 2023 -- A meta-analysis has linked the administration of convalescent plasma to a reduced rate of hospitalization for COVID-19, suggesting that the readily accessible treatment could play an important role in a future viral pandemic. Read More
FDA issues draft guidance for implementing decentralized clinical trials
May 2, 2023 -- The U.S. Food and Drug Administration (FDA) on Tuesday said that it is taking additional steps to support the use of decentralized clinical trials (DCTs) for drugs, biologics, and devices, where some or all the trial-related activities occur at locations other than traditional clinical trial sites. Read More
Specialized printer may help vaccines reach more people
April 24, 2023 -- Researchers have developed a specialized printer to generate vaccine-filled microneedle skin patches that can be stored long-term without refrigeration. Their research, published Monday in Nature Biotechnology, may eventually bring more vaccines to more people. Read More
Pfizer, Thermo Fisher Scientific collaborate to broaden access to NGS testing in underserved countries
May 9, 2023 -- Pfizer and Thermo Fisher Scientific on Tuesday announced they have entered into a collaboration agreement to help increase local access to next-generation sequencing (NGS)-based testing for lung and breast cancer patients in more than 30 countries. Read More
An unprecedented view of gene regulation
May 8, 2023 -- Massachusetts Institute of Technology (MIT) engineers have developed a technique to analyze the organization of the genome at a resolution 100 times higher than was previously possible. Read More
HBV vaccine developer Hookipa Pharma granted $5 million milestone payment under agreement with Gilead
January 4, 2023 -- Hookipa Pharma, the developer of a new class of immunotherapies using an arenavirus platform, on Wednesday announced that it has been granted a $5 million milestone payment under a collaboration agreement with Gilead Sciences. Read More
Exhausted cancer-killing cells help tumors by suppressing the immune system, study finds
December 21, 2022 -- Exhausted T cells switch from attacking to helping cancers in low-oxygen environments, pointing to a new way to improve the efficacy of immuno-oncology drugs, according to a study published on Wednesday in Nature Immunology. Read More
Boosting TERRA levels damages DNA of hard-to-kill cancer cells: study
September 20, 2022 -- Increasing levels of telomeric repeat-containing RNA (TERRA) damages the DNA of cancers with a particular form of replicative immortality and leads to cell death, according to Portuguese researchers who show that “anti-aging clocks” can be used to kill cancer cells. Read More
Scientists pinpoint why alveolar macrophages don’t develop properly
September 19, 2022 -- Researchers in Germany have solved the mystery of what prevents alveolar macrophages from developing properly: the transcription factor CCAAT/enhancer binding protein beta (C/EBPβ). Read More
Single DNA strand cuts achieve safety and efficacy edge over CRISPR-Cas9 in fruit flies
July 5, 2022 -- CRISPR-Cas9 variants known as “nickases” that target a single DNA strand may increase the success rate of gene editing and reduce the risk of off-target mutations, according to a paper published in the journal Science Advances. Read More
Ga. researchers combine DNA barcoding, target sequencing
July 5, 2022 -- Researchers in Georgia have developed a system to make preclinical nanoparticle studies more predictive that combines DNA barcoding with a multiomic nanoparticle delivery system called single-cell nanoparticle targeting-sequencing. Read More
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